@article {4808,
	title = {Dengue virus transmission from live donor liver graft},
	year = {2019},
	month = {Jan},
	abstract = {Arboviral transmission through transplanted organs is rare. We report a highly probable case of dengue viral transmission during live donor liver transplantation. Fever with severe thrombocytopenia was observed in the donor and recipient within 6 and 9 days after transplantation, respectively. Dengue diagnosis was confirmed by testing blood and explant tissue from the donor and recipient using dengue-specific NAT (nucleic acid testing) and serology. Serology indicated the donor had secondary dengue infection that ran a mild course. However, the dengue illness in the recipient was severe and deteriorated rapidly, eventually proving fatal. The recipient{\textquoteright}s explant liver tissue tested negative for viral RNA indicative of a pretransplant na{\"\i}ve status. The prM-Envelope gene sequence analysis of the donor and recipient viral RNA identified a similar serotype (DENV1) with almost 100\% sequence identity in the envelope region. Molecular phylogenetic analysis of donor and recipient viral envelope sequences with regional and local dengue strains further confirmed their molecular similarity, suggesting a probable donor-to-recipient transmission via organ transplantation. Screening of living donors for dengue virus may be considered in endemic regions.},
	doi = {10.1111/ajt.15270},
	author = {Shaji Mathew, J and Menon, VP and Menon, VP and Mallick, S and Sivasankara Pillai Thankamony Amma, B and Balakrishnan, D and Gopalakrishnan, U and Narayana Menon, R and Athira, PP and Jagan, OA and Surendran, S}
}
