@article {4917,
	title = {Risk of adverse maternal and fetal outcomes during pregnancy in living kidney donors: A matched cohort study},
	volume = {33},
	year = {2019},
	month = {Jan},
	pages = {e13453},
	abstract = {Background: We examined the risk of adverse pregnancy outcomes in primiparous kidney donors compared to matched controls.

Methods: Fifty-nine women with a history of kidney donation prior to their first pregnancy with normal renal function and no history of kidney disease, diabetes or chronic hypertension were matched 1:4 by age (within 2 years) and race to women with two kidneys using data from an integrated healthcare delivery system. Adverse pregnancy outcomes were defined as preterm delivery (delivery <37 weeks), delivery via cesarean section, gestational hypertension, preeclampsia/eclampsia, gestational diabetes, length of stay in the hospital >3 days, infant death/transfer to acute facility and low birthweight (<2500 g).

Results: Living kidney donors did not have a higher risk of adverse outcomes compared to matched controls. There was a trend toward an increased risk of preeclampsia/eclampsia in kidney donors but it did not reach statistical significance (Odds ratio [OR]: 2.96, 95\% CI: 0.98-8.94, P = 0.06). However, in kidney donors <=30 years of age, there was a fourfold increased risk of preeclampsia/eclampsia (OR: 4.09, 95\% CI: 1.07-15.59, P = 0.04).

Conclusion: Overall, the risk of pregnancy-associated complications following kidney donation is small but potential female kidney donors should be counseled on the possible increased risk of preeclampsia.},
	doi = {10.1111/ctr.13453},
	author = {Davis, S and Dylewski, J and Shah, PB and Holmen, J and You, Z and Chonchol, M and Kendrick, J}
}
