@article {455,
	title = {Renal transplantation exposes patients with previous Kaposi{\textquoteright}s sarcoma to a high risk of recurrence},
	journal = {Transplantation},
	volume = {62},
	year = {1996},
	note = {0041-1337 (Print) Case Reports Journal Article Review},
	month = {Aug 27},
	pages = {463 - 6},
	abstract = {It is currently estimated that about 0.5\% of patients will develop Kaposi{\textquoteright}s sarcoma (KS) after kidney transplantation. Tapering of immunosuppression often leads to KS remission, but also results in graft loss in more than 50\% of cases. Whether retransplantation is safe in these patients is unknown. We here report on eight patients who developed KS recurrence after kidney transplantation-(A) Patients with previously treated KS: There were 4 patients who had clinical remission of KS (including three posttransplantation) for periods ranging from 5 months up to 19 years before transplantation. All 4 developed KS recurrence within months after transplantation. In 3 patients, KS regressed only when all immunosuppression was discontinued, at the price of allograft removal. Partial remission occurred in the fourth patient following reduction of immunosuppression and gancyclovir administration; (B) Patients with recurrent KS during a single transplant: 4 patients developed KS after transplantation that regressed following reduction of immunosuppressive therapy. Increased immunosuppression, in the form of steroid pulses in 3 patients was associated with recurrence of KS. Subsequent reduction of immunosuppression caused regression of KS in all 4 patients, but 2 recipients lost their allografts. These data emphasize the high risk of recurrence of KS after renal transplantation. If physicians decide to transplant patients with a history of KS, they should inform the future recipient of the possibility of KS recurrence.},
	keywords = {Adult, Female, Humans, Immunocompromised Host, Kidney Transplantation / *adverse effects, Male, Middle Aged, Recurrence, Research Support, Non-U.S. Gov{\textquoteright}t, Risk Factors, Sarcoma, Kaposi / *complications},
	author = {Doutrelepont,J. M. and De Pauw,L. and Gruber,S. A. and Dunn,D. L. and Qunibi,W. and Kinnaert,P. and Vereerstraeten,P. and Penn,I. and Abramowicz,D.}
}
