@article {649,
	title = {Eye-banking risk factors for fungal endophthalmitis compared with bacterial endophthalmitis after corneal transplantation},
	journal = {Am J Ophthalmol},
	volume = {139},
	year = {2005},
	note = {Hassan, Sohela S Wilhelmus, Kirk R Medical Review Subcommittee of the Eye Bank Association of America P30 EY02520/EY/NEI NIH HHS/United States T32 EY07001/EY/NEI NIH HHS/United States Comparative Study Research Support, Non-U.S. Gov{\textquoteright}t Research Support, U.S. Gov{\textquoteright}t, P.H.S. United States American journal of ophthalmology},
	month = {Apr},
	pages = {685 - 90},
	edition = {38448},
	abstract = {PURPOSE: To track the relative frequency and explore possible risk factors of fungal compared with bacterial endophthalmitis after corneal transplantation. DESIGN: Case-comparison study nested in a surveillance registry. METHODS: We examined, among recipients who underwent surgery from January 1991 through December 2003, demographic and eye-banking characteristics of postkeratoplasty endophthalmitis cases that were reported to the Eye Bank Association of America by US eye banks. Potential predictors of fungal compared with bacterial endophthalmitis were examined using multiple logistic regression. RESULTS: Of 234 reported cases of postkeratoplasty endophthalmitis reported by US eye bank, 46 cases (19.7\%) were fungal, and 130 cases (55.6\%) were bacterial. Concordant cultures of the residual donor corneoscleral rim or preservation medium occurred significantly more often with fungal than bacterial endophthalmitis (P = .009). After the introduction of Optisol-GS, the odds of bacterial relative to fungal endophthalmitis decreased by 77\% (95\% confidence interval, 44\% - 91\%). After adjustment for the preservation method and other eye-banking variables, the odds of fungal endophthalmitis was 3.4 (95\% confidence interval, 1.6 - 7.4) times that of bacterial endophthalmitis, when donor corneal preservation was 4 days or longer. CONCLUSIONS: The frequency of postkeratoplasty bacterial endophthalmitis compared with fungal endophthalmitis fell after widespread use of a corneal preservation medium supplemented with gentamicin and streptomycin. Further improvements in corneal preservation procedures are needed.},
	keywords = {*Corneal Transplantation, *Postoperative Complications, Aged, Cause of Death, Endophthalmitis / *epidemiology / *microbiology, Eye Banks / *statistics \& numerical data, Eye Infections, Bacterial / *epidemiology / etiology, Eye Infections, Fungal / *epidemiology / etiology, Humans, Middle Aged, Odds Ratio, Organ Preservation / methods, Registries / statistics \& numerical data, Risk Factors, Tissue Donors, United States / epidemiology},
	issn = {0002-9394 (Print) 0002-9394 (Linking)},
	doi = {S0002-9394(04)01497-7 [pii] 10.1016/j.ajo.2004.12.016},
	url = {internal-pdf://Hassan - Eye banking risk factors fungal-2476677120/Hassan - Eye banking risk factors fungal.pdf},
	author = {Hassan,S. S. and Wilhelmus,K. R.}
}
