@article {674,
	title = {A poorly differentiated lymphoma of donor origin in a renal allograft recipient},
	journal = {Transplantation},
	volume = {47},
	year = {1989},
	note = {Hjelle, B Evans-Holm, M Yen, T S Garovoy, M Guis, M Edman, J C Case Reports Research Support, Non-U.S. Gov{\textquoteright}t United states Transplantation Transplantation. 1989 Jun;47(6):945-8.},
	month = {Jun},
	pages = {945 - 8},
	edition = {32660},
	abstract = {Malignant lymphoma is a frequent complication of organ transplantation. It has been suggested that such tumors arise as a result of uncontrolled proliferation of Epstein-Barr virus-infected B lymphocytes in an immunosuppressed host. Although a few cases of posttransplant lymphomas in bone marrow transplantation have been shown to be of donor cell origin, no recipients of solid-organ transplants are known to have developed lymphomas arising from donor cells. In this report, a case of diffuse high-grade lymphoma that apparently arose in the allograft of a renal transplant recipient is described. DNA fingerprinting demonstrated the tumor to be of donor origin; Epstein-Barr sequences were absent. A therapeutic trial consisting of withdrawal of immunosuppressive agents and administration of acyclovir was unsuccessful. These data support the notion that donor cells can undergo malignant transformation in solid-organ transplant recipients, and such tumors need not carry EBV genetic material.},
	keywords = {*Kidney Transplantation, *Tissue Donors, Adolescent, B-Lymphocytes / pathology, Cell Differentiation, Humans, Immunoglobulin Joining Region / genetics, Lymphoma / *etiology / genetics / pathology, Male, Nucleic Acid Hybridization, Postoperative Complications / etiology / pathology, Transplantation, Homologous / adverse effects},
	issn = {0041-1337 (Print) 0041-1337 (Linking)},
	author = {Hjelle,B. and Evans-Holm,M. and Yen,T. S. and Garovoy,M. and Guis,M. and Edman,J. C.}
}
