@article {729,
	title = {A comparison of patellar tendon autograft and allograft used for anterior cruciate ligament reconstruction in the goat model},
	journal = {Am J Sports Med},
	volume = {21},
	year = {1993},
	note = {Jackson, D W Grood, E S Goldstein, J D Rosen, M A Kurzweil, P R Cummings, J F Simon, T M Comparative Study Research Support, Non-U.S. Gov{\textquoteright}t United states The American journal of sports medicine},
	month = {Mar-Apr},
	pages = {176 - 85},
	edition = {34029},
	abstract = {Similar-sized patellar tendon autografts and fresh-frozen allografts were used to reconstruct the anterior cruciate ligament of one knee in 40 female goats. Evaluations of the reconstructions and contralateral controls at the 6-week and 6-month postoperative periods included anterior-posterior translation, mechanical properties determined during tensile failure tests, measurement of cross-sectional area, histology, collagen fibril size and area distribution, and associated articular cartilage degenerative changes. Six months after anterior cruciate ligament reconstruction, the autografts demonstrated a smaller increase in anterior-posterior displacement, values of maximum force to failure two times greater, a significant increase in cross-sectional area, a more rapid loss of large-diameter collagen fibrils, and an increased density and number of small-diameter collagen fibrils compared to the allografts. Clinical significance. More surgeons are allowing their patients to return to running and sports 6 months after anterior cruciate ligament reconstruction. While the structural and material properties of autografts and allografts at time zero are similar, in the goat model during the first 6 months they differ. The allografts demonstrate a greater decrease in their implantation structural properties, a slower rate of biologic incorporation, and the prolonged presence of an inflammatory response. At 6 months the autograft demonstrates a more robust biologic response, improved stability, and increased strength to failure values.},
	keywords = {Animals, Anterior Cruciate Ligament / *injuries / *surgery, Collagen, Female, Goats, Hindlimb / surgery, Microscopy, Electron, Tendons / pathology / *transplantation, Time Factors, Transplantation, Autologous, Transplantation, Homologous},
	issn = {0363-5465 (Print) 0363-5465 (Linking)},
	author = {Jackson,D. W. and Grood,E. S. and Goldstein,J. D. and Rosen,M. A. and Kurzweil,P. R. and Cummings,J. F. and Simon,T. M.}
}
