@article {839,
	title = {Pelvic magnetic resonance imaging after bone marrow harvest a retrospective study in 50 unrelated marrow donors},
	journal = {Bone Marrow Transplantation},
	volume = {35},
	year = {2005},
	note = {HPC},
	month = {Apr},
	pages = {667 - 673},
	abstract = {A total of 50 unrelated marrow donors were examined by pelvic magnetic resonance imaging (MRI) to investigate the morphological sequelae of bone marrow harvesting (BMH). Signal increase in T2-weighted sequences and contrast media enhancement in T1 sequences at the operative sites were found as typical MRI morphology 4 weeks after harvest (group A, n = 16), corresponding to edema, hyperemia and proliferative activity. Although tissue repair was completed in the majority of donors 1 year after BMH, about 36\% of donors in group B (n = 16) had abnormal findings. These included a persistence of the {\textquoteright}acute injury{\textquoteright} signal pattern (2/16, 12\%), and signal alterations due to fatty marrow conversion (4/16, 24\%). The proportion of MRI abnormalities increased to over 70\% in two-time donors ( group C, n = 11), which might indicate a cumulation of tissue damage after repetitive harvests. If donors had experienced prolonged discomfort after BMH (group D, n = 7), MRI revealed pathological signals in 86\%. In conclusion, the MRI morphology reflects the pathophysiological reactions after BMH, including inflammation and tissue repair. A further prospective evaluation in a larger number of donors is necessary to confirm these results and to identify the factors which influence the extent and duration of tissue damage.},
	author = {Kroschinsky,F. and Kittner,T. and Mauersberger,S. and Rautenberg,U. and Schuler,U. and Rutt,C. and Laniado,M. and Ehninger,G.}
}
