@article {935,
	title = {Acute life-threatening cardiovascular toxicity with umbilical cord blood infusion: the role of dextran.},
	journal = {Am J Hematol},
	volume = {85},
	year = {2010},
	month = {Sep},
	pages = {722 - 4},
	abstract = {Umbilical cord blood (UCB) is being increasingly used for hematopoietic stem cell transplantation due to its immediate availability. Dimethylsulfoxide (DMSO) and dextran-40 are commonly used for processing and cryopreservation of UCB. Adverse UCB infusion-related events are usually mild. However, reports of severe life-threatening events are now emerging. DMSO has been proposed as a possible cause of infusion-related reactions. In this report, we draw attention to an acute near-fatal reaction with UCB infusions resulting in myocardial ischemia and acute renal failure. We propose that dextran-40 in UCB infusion products be considered as a potential causative agent contributing to this infusion-related reaction, based on reports of known adverse reactions to dextran-40 in non-transplant settings.},
	keywords = {Adult, Aged, Cord Blood Stem Cell Transplantation, Dextrans, Female, Hematologic Neoplasms, Humans, Male, Middle Aged, Myocardial Ischemia, Plasma Substitutes, Transplantation, Homologous},
	issn = {1096-8652},
	doi = {10.1002/ajh.21797},
	author = {Ma,RW and Kwan,JM and Ma,DD and Fay,KC}
}
