@article {1429, title = {Human T-cell leukemia virus type I-associated myelopathy following living-donor liver transplantation}, journal = {Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society}, volume = {14}, year = {2008}, note = {Soyama, Akihiko Eguchi, Susumu Takatsuki, Mitsuhisa Ichikawa, Tatsuki Moriuchi, Masako Moriuchi, Hiroyuki Nakamura, Tatsufumi Tajima, Yoshitsugu Kanematsu, Takashi Liver Transpl. 2008 May;14(5):647-50.}, month = {May}, pages = {647 - 50}, type = {Case Reports}, edition = {39563}, abstract = {This report describes a patient who developed human T-cell leukemia virus type I-associated myelopathy (HAM) following a living-donor liver transplantation (LDLT) for liver cirrhosis due to hepatitis C virus (HCV) infection. Both the recipient and the living donor (his sister) were human T-cell leukemia virus type I (HTLV-I) carriers. Since the LDLT, he had been treated with immunosuppressive drugs such as tacrolimus and steroids as well as interferon-alpha to prevent rejection and a recurrence of the HCV infection, respectively. Even though the HTLV-I proviral load had decreased upon interferon treatment, he developed a slowly progressive gait disturbance with urinary disturbance 2 years after the LDLT and was diagnosed with HAM. This appears to be the first report of HAM development in an HLTV-I-infected LDLT recipient.}, keywords = {*Living Donors, Antiviral Agents / therapeutic use, Drug Therapy, Combination, Gait Disorders, Neurologic / etiology, Graft Rejection / prevention \& control, Hepatitis C / *complications / surgery, Humans, Immunosuppressive Agents / therapeutic use, Interferon Alfa-2b / therapeutic use, Liver Cirrhosis / *surgery / virology, Liver Transplantation / *adverse effects, Male, Middle Aged, Paraparesis, Tropical Spastic / complications / drug therapy / *etiology, Steroids / therapeutic use, Tacrolimus / therapeutic use, Treatment Outcome, Urination Disorders / etiology}, issn = {1527-6473 (Electronic) 1527-6465 (Linking)}, doi = {10.1002/lt.21414}, author = {Soyama,A. and Eguchi,S. and Takatsuki,M. and Ichikawa,T. and Moriuchi,M. and Moriuchi,H. and Nakamura,T. and Tajima,Y. and Kanematsu,T.} }