@article {1608, title = {Pure red cell aplasia due to parvovirus B19 infection transmitted probably through hematopoietic stem cell transplantation}, journal = {Transplant infectious disease : an official journal of the Transplantation Society}, volume = {10}, year = {2008}, note = {Wasak-Szulkowska, E Grabarczyk, P Rzepecki, P Denmark Transpl Infect Dis. 2008 Jun;10(3):201-5. Epub 2007 Jul 12.}, month = {Jun}, pages = {201 - 5}, type = {Case Reports}, edition = {39280}, abstract = {Human parvovirus B19 is a very common infectious pathogen in humans. In healthy subjects, B19 infection is the cause of a self-limiting subclinical erythroid aplasia, followed by rash or arthralgia. In immunocompromised patients B19 can cause chronic anemia. This report presents the case of a 19-year-old male who developed severe anemia shortly after successful allogeneic hematopoietic stem cell transplantation. His marrow showed selective erythroid aplasia, and real-time polymerase chain reaction assay confirmed parvovirus B19 infection. Despite repeated high-dose immunoglobulin treatment, he remained anemic. His hematological status markedly improved after cessation of immunosuppression. Retrospective examination of the donor{\textquoteright}s blood suggests that hematopoietic stem cells could be the source of infection.}, keywords = {*Parvovirus B19, Human, Adult, DNA, Viral / analysis, Hematopoietic Stem Cell Transplantation / *adverse effects, Humans, Male, Parvoviridae Infections / complications / therapy / *transmission, Red-Cell Aplasia, Pure / *etiology}, issn = {1399-3062 (Electronic) 1398-2273 (Linking)}, doi = {10.1111/j.1399-3062.2007.00266.x}, author = {Wasak-Szulkowska,E. and Grabarczyk,P. and Rzepecki,P.} }