@article {4135,
	title = {Delayed hemolytic transfusion reaction due to anti-S antibody in patient with anti-Jk(a) autoantibody and multiple alloantibodies.},
	journal = {Annals of hematology//Ann Hematol},
	volume = {83},
	year = {2004},
	month = {2004},
	pages = {307 - 8},
	publisher = {Guastafierro,S. Department of Hematology, Transfusion Medicine and Transplant Immunology, Second University of Naples, Naples, Italy.},
	address = {Germany},
	abstract = {We describe the case of a 60-year-old woman with a delayed hemolytic transfusion reaction (DHTR). She had a history of an ulcerative colitis, blood transfusion because of rectal bleeding, and surgical removal of descendent and sigmoid colon. At admission, laboratory data showed Hb 6.3 g/dL, reticulocytes 120 x 10(9)/L, serum total bilirubin 1.2 mg/dL (direct bilirubin: 0.2 mg/dL). Pretransfusion antibody screening procedures were positive. A monospecific autoanti-Jk(a) and three alloantibodies (anti-c, -E, -K) were identified by immunohematologic studies. The patient received two units of crossmatch compatible concentrated red blood cells. Six days later biochemical serum values showed Hb 6.2 g/dL, LDH 975 I.U./L and total bilirubin 2.95 mg/dL (direct 0.35 mg/dL). Crossmatches with red cell suspension of transfused blood units and a post-transfusion serum were repeatedly positive. Laboratory tests showed the presence of anti-S alloantobody in the serum and eluate. Moreover, pre-transfusion serum of the patient was retrospectively retested: anti-S was not detected. These data suggested a DHTR. The present case is unusual and interesting because of the association of a rare autoanti-Jk(a), non responsible for anemia, and four alloantibodies of which anti-S involved in a DHTR.},
	keywords = {*Autoantibodies/im [Immunology], *Blood Transfusion/ae [Adverse Effects], *Hemolysis/im [Immunology], *Isoantibodies/im [Immunology], *Kidd Blood-Group System/im [Immunology], *MNSs Blood-Group System/im [Immunology], Autoantibodies/bl [Blood], Female, Humans, Isoantibodies/bl [Blood], Middle Aged, Time Factors},
	isbn = {0939-5555},
	author = {Guastafierro, S and Sessa, F and Cuomo, C and Tirelli, A}
}
