@article {4136,
	title = {Anti-s Antibody-Associated Delayed Hemolytic Transfusion Reaction in Patients With Sickle Cell Anemia.},
	journal = {//J Pediatr Hematol Oncol},
	volume = {21},
	year = {1999},
	month = {1999},
	pages = {70 - 73},
	publisher = {From the Department of Pediatrics, Children{\textquoteright}s Hospital of Michigan, Wayne State University, Detroit, MI 48201.},
	address = {(C) 1999 Lippincott Williams \& Wilkins, Inc.},
	abstract = {Purpose: Signs and symptoms of delayed hemolytic transfusion reaction (DHTR) may resemble those of vaso-occlusive crises in patients with sickle cell anemia (SCA). The diagnosis of DHTR therefore presents a challenge to the clinician when treating such patients. The current study describes a patient with SCA and DHTR secondary to red cell anti-s antibody, manifesting as painful extremeties, severe hemolytic anemia, and acute oliguric renal failure., Patient and Methods: A 17-year-old patient with homozygous hemoglobin S presented 8 days after partial exchange transfusions with severe anemia and signs and symptoms resembling vaso-occlusive crisis. Clinical course was complicated by intravascular hemolysis and acute renal failure., Results: Anti-s antibody was detected in the eluate. Diagnosis of DHTR was made. Treatment included single volume whole blood exchange transfusion and continuous veno-venous hemofiltration with dialysis., Conclusions: The possibility of DHTR should be considered in a patient with SCA with hemolytic anemia. Acute renal failure is a rare complication of anti-s antibody-associated DHTR. Such reactions can be successfully managed with exchange transfusion and continuous hemofiltration with dialysis., (C) 1999 Lippincott Williams \& Wilkins, Inc.},
	keywords = {Direct anti-globulin test., Hemolytic transfusion reactions, Sickle cell anemia},
	isbn = {1077-4114},
	author = {Kalyanaraman, Meena and Heidemann, Sabrina and Sarnaik, Ashok and Meert, Kathleen and Sarnaik, Sharada}
}
