@article {4190,
	title = {Severe hemolytic transfusion reaction due to anti-D in a D+ patient with sickle cell disease.},
	journal = {Journal of pediatric hematology/oncology//J Pediatr Hematol Oncol},
	volume = {37},
	year = {2015},
	month = {2015},
	pages = {e135 - 7},
	publisher = {Ipe,Tina S. *Department of Pathology, Houston Methodist Hospital, Houston, TX Departments of +Pediatrics Pathology and Laboratory Medicine, The Children{\textquoteright}s Hospital of Philadelphia, Philadelphia, PA ++Immunohematology and Genomics Laboratory, New York Bloo},
	address = {United States},
	abstract = {A 5-year-old male with sickle cell disease presented with pain, dark urine, and fatigue 10 days after a red blood cell (RBC) transfusion. Laboratory evaluation demonstrated severe anemia, blood type O+, and anti-D in the serum. Anti-D in a D+ patient led to RH genotyping, which revealed homozygosity for RHD*DAU4 that encodes partial D antigen. Anti-D in this patient whose RBCs exclusively express partial D caused a delayed hemolytic transfusion reaction after exposure to D+ RBCs. The finding of anti-D in a D+patient should be investigated by molecular methods to help distinguish an alloantibody from an autoantibody.},
	isbn = {1536-3678},
	author = {Ipe, Tina S and Wilkes, Jennifer J and Hartung, Helge D and Westhoff, Connie M and Chou, Stella T and Friedman, David F}
}
