@article {4231,
	title = {The first reported case of anti-Dob causing an acute hemolytic transfusion reaction.},
	journal = {Vox sanguinis//Vox Sang},
	volume = {66},
	year = {1994},
	month = {1994},
	pages = {206 - 9},
	publisher = {Halverson,G. Blood Bank and Transfusion Service, New York Hospital-Cornell Medical Center, New York, NY 10021.},
	address = {SWITZERLAND},
	abstract = {The antibodies of the Dombrock blood group system have only rarely been encountered in transfusion practice, and anti-Dob has not previously been implicated in an acute hemolytic transfusion reaction. We have encountered the first such case involving a chronically transfused black female with hemoglobin SS disease and multiple antibodies in her serum. During a previous admission for sickle cell crisis, the patient received 3 units of compatible blood with no untoward effects. Serum obtained 21 days later contained, in addition to the known antibodies, anti-S plus an unidentified antibody showing characteristics of HTLA. Blood lacking the E, K1, Fy(a), Jk(b) and S antigens was obtained, and 2 least incompatible units were transfused. While administering the second unit, the patient complained of fever and low back pain, and hemoglobinemia was detected. Anti-Dob was identified in the post-reaction samples by absorption-elution tests, and the patient was confirmed to be Do(a+b-). The first unit transfused during this hemolytic episode tested Do (b+). This case, and a similar case involving anti-Doa reported in 1986, strengthens the belief that Dombrock antibodies are clinically significant and illustrates the need for their differentiation, prior to transfusion from less clinically significant HTLA antibodies.},
	keywords = {*Blood Transfusion/ae [Adverse Effects], *Hemolysis/im [Immunology], *Isoantibodies/im [Immunology], Acute Disease, Adult, Anemia, Sickle Cell/th [Therapy], Female, Humans},
	isbn = {0042-9007},
	author = {Halverson, G and Shanahan, E and Santiago, I and Mabile, R and Thurrell, T and Strupp, A M and Wolf, C F and Spruell, P and Moulds, M K}
}
