@article {4358,
	title = {Total and allergen-specific IgE in relation to allergic response pattern following bone marrow transplantation.},
	journal = {Clinical and experimental immunology//Clin Exp Immunol},
	volume = {66},
	year = {1986},
	month = {1986},
	pages = {633 - 9},
	address = {ENGLAND},
	abstract = {Total and allergen-specific serum IgE were measured in relation to allergic response pattern before and after bone marrow transplant (BMT) in seven sibling donor/recipient pairs. Two non-atopic recipients developed persistently raised total serum IgE levels but no apparent allergic response after BMT from non-atopic donors; three non-atopic recipients showed raised total serum IgE after BMT, with allergen-specific IgE to the same allergens as their respective atopic donors. A penicillin-tolerant recipient showed clinical sensitivity and specific IgE to penicillin after BMT from a penicillin-sensitive donor, but with this case both donor and recipient showed raised serum IgE levels. One atopic recipient showed decreased total IgE after BMT from a mildly atopic donor. These allergic response patterns could occur as a result of repopulation in the recipient with IgE-specific T lymphocytes having similar regulatory influences as in the donor. The pattern of acquired responses would also be consistent with reconstitution by primed B lymphocytes of donor origin.},
	keywords = {*Bone Marrow Transplantation, *Hypersensitivity/im [Immunology], *Immunoglobulin E/an [Analysis], Adolescent, Adult, Allergens/im [Immunology], Child, Child, Preschool, Epitopes/im [Immunology], Female, Humans, Infant, Male, Radioallergosorbent Test},
	isbn = {0009-9104},
	author = {Walker, S A and Riches, P G and Wild, G and Ward, A M and Shaw, P J and Desai, S and Hobbs, J R}
}
