@article {4361,
	title = {Factor XII Deficiency Acquired by Orthotopic Liver Transplantation: Case Report and Review of the Literature.},
	journal = {//Am J Transplant},
	volume = {6},
	year = {2006},
	month = {2006},
	pages = {1743 - 1745},
	publisher = {(a)Transplant Center, Mayo Clinic College of Medicine, Rochester, Minnesota, USA(b)Divsion of Hematology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA},
	address = {Copyright (C) 2006 Blackwell Publishing Ltd.},
	abstract = {Transmission of congenital clotting factor deficiencies after orthotopic liver transplantation is rare. There are published reports of liver donor-to-recipient transmission of protein C deficiency with dysfibrinogenemia, protein S, factor VII and factor XI deficiencies. We report a case of transmission of factor XII deficiency with liver transplantation in a patient with Budd-Chiari syndrome. There was a persistent elevation of the activated partial thromboplastin time (aPTT), but no evidence of bleeding while the patient was maintained on warfarin. The presence of a persistently abnormal aPTT may raise suspicion for the presence of a clotting factor deficiency; however, deficiencies of other clotting factors may not be readily apparent on routine blood tests performed in a donor. Being aware of the possibilities of transmission of these inherited deficiencies of coagulation factors will aid in their early detection and management in the transplant donor and recipient., Copyright (C) 2006 Blackwell Publishing Ltd.},
	keywords = {Budd-Chiari syndrome, clotting factors, coagulation, factor XII deficiency, hypercoagulable},
	isbn = {1600-6135},
	author = {Osborn, N. and Ustundag, Y. and Zent, C. and Wiesner, R. and Rosen, C. and Narayanan Menon, K.}
}
