01711nas a2200181   4500008003900000245009700039210006900136260000800205300000600213490000700219520117700226100001601403700001701419700001401436700001501450700001501465856004901480       2004                          d00aPatients with primary brain tumors as organ donors: case report and review of the literature0 aPatients with primary brain tumors as organ donors case report a  cJul  a30 v433 aMalignancy is considered a contra-indication to organ donation, with a few possible exceptions. We present the case of a child with fatal intracranial hemorrhage from a primary brain tumor (PBT) whose organs were denied for transplant after recovery. We review the literature of organ donors with PBTs in the context of the current organ shortage and discuss the implications for the practicing oncologist. Transmission of donor brain tumor to organ recipients has been documented but the incidence appears to be very low. Risk factors for tumor transmission include underlying donor tumor histology, history of craniotomy and/or shunt placement, use of systemic chemotherapy and radiation therapy, and duration of disease prior to donation. Ongoing data collection by national registries will provide more information on the potential risk to organ recipients. It may be appropriate to expand the donor pool to include donors with PBTs in certain situations. The transplantation team ultimately decides upon the use of organs from specific donors. Many families will appreciate the opportunity to donate specific tissues even if solid organ transplantation is prohibited.1 aPunnett, AS1 aMcCarthy, LJ1 aDirks, PB1 aHawkins, C1 aBouffet, E  uhttps://www.notifylibrary.org/reference/4709