01431nas a2200157   4500008004300000245013500043210006900178520088400247100001501131700001401146700001801160700001401178700001701192700001501209856004901224       Submitted                       d  00aDisseminated Tuberculosis in an Immunocompetent Patient Associated With the Use of Contaminated Bone Matrix Graft in Spine Surgery0 aDisseminated Tuberculosis in an Immunocompetent Patient Associat3 aMiliary tuberculosis (TB) is a rare and potentially fatal form of disseminated TB. Disseminated TB involving the central nervous system (CNS) may be seen in up to nearly a third of miliary TB cases. We describe a case of miliary TB with CNS involvement and suspected hepatobiliary involvement in an immunocompetent patient after an elective spine surgery. Given the patient's unusual presentation in the absence of risk factors for TB, diagnosis was delayed. We were later informed that the bone graft he received during spine surgery, FiberCel ("FiberCel") Fiber Viable Bone Matrix (Aziyo Biologics, Inc, Richmond, Calif), was contaminated with TB. This patient is 1 of almost 2 dozens reported to be affected. This case represents a novel presentation of TB due to contaminated cadaveric bone allograft matrix implantation, with notable rapid dissemination and CNS involvement.1 aCullen, GD1 aTabaja, H1 aOgbonna, C, P1 aMenze, AK1 aEscalante, P1 aWilson, JW  uhttps://www.notifylibrary.org/reference/5045