01232nas a2200157   4500008003900000245007100039210006900110300001200179490000700191520076600198100001800964700001500982700001300997700001501010856004901025       2021                          d00aFatal donor-derived Kaposi sarcoma following liver transplantation0 aFatal donorderived Kaposi sarcoma following liver transplantatio  ae2360610 v223 aHuman herpesvirus-8 (HHV8) is a recognised precursor for a number of neoplastic and non-neoplastic processes. Immunosuppressed recipients of both solid organ and haematopoietic stem cell transplants are at risk of life-threatening lytic reactivations of HHV8-infected B-lymphocytes, primary infections after receiving grafts from HHV8-seropositive donors and more rarely by the direct transplantation of malignant Kaposi sarcoma cells seeded within graft tissue. We describe the case of an HHV8-seronegative patient with confirmed, post-orthotopic liver transplant transmission of HHV8 from a seropositive donor with quantitative evidence of viraemia and subsequent development of disseminated visceral and cutaneous Kaposi sarcoma with a rapidly fatal outcome.1 aCopeland, MMM1 aTrainor, J1 aCash, WJ1 aBraniff, C  uhttps://www.notifylibrary.org/reference/5074