01945nas a2200217   4500008003900000245010700039210006900146300000700215490000700222520131400229100001501543700001301558700001301571700001401584700001601598700001801614700001601632700001401648700001601662856004901678       2020                          d00aPathological features and outcomes of incidental renal cell carcinoma in candidate solid organ donors.0 aPathological features and outcomes of incidental renal cell carc  a870 v393 aBackground
We report the findings of a single Italian center in the evaluation of renal lesions in deceased donors from 2001 to 2017. In risk evaluation, we applied the current Italian guidelines, which include donors with small (< 4 cm, stage pT1a) renal carcinomas in the category of non-standard donors with a negligible risk of cancer transmission.

Methods
From the revision of our registries, 2,406 donors were considered in the Emilia Romagna region of Italy; organs were accepted from 1,321 individuals for a total of 3,406 organs.

Results
The evaluation of donor safety required frozen section analysis for 51 donors, in which a renal suspicious lesion was detected by ultrasound. Thirty-two primary renal tumors were finally diagnosed 26 identified by frozen sections and 6 in discarded kidneys. The 32 tumors included 13 clear cell renal cell carcinomas (RCCs), 6 papillary RCCs, 6 angiomyolipomas, 5 oncocytomas, 1 chromophobe RCC, and 1 papillary adenoma. No cases of tumor transmission were recorded in follow-up of the recipients.

Conclusion
Donors with small RCCs can be accepted to increase the donor pool. Collaboration in a multidisciplinary setting is fundamental to accurately evaluate donor candidate risk assessment and to improve standardized protocols for surgeons and pathologists.1 aAmbrosi, F1 aRicci, C1 aMalvi, D1 aCillia, C1 aRavaioli, M1 aFiorentino, M1 aCardillo, M1 aVasuri, F1 aA, D'Errico  uhttps://www.notifylibrary.org/reference/5090