02850nas a2200361   4500008004100000022004700041245009000088210006900178250001000247260000800257300001300265490000700278520176900285653001902054653003602073653001502109653001002124653000902134653001902143653001102162653002202173653001102195653002402206653005302230653000902283653001602292653002602308653005902334653001602393100001602409700001502425856004802440       2010                        eng d  a1523-6838 (Electronic) 0272-6386 (Linking)00aThe impact of nonidentical ABO deceased donor kidney transplant on kidney utilization0 aimpact of nonidentical ABO deceased donor kidney transplant on k  a40267  cJul  a95 - 1010 v563 aBACKGROUND: Blood type AB kidney transplant candidates have the shortest waiting times, yet the current allocation system allows allocation of type A donor kidneys to type AB recipients. STUDY DESIGN: United Network for Organ Sharing/Organ Procurement and Transplantation Network data between 1995 and 2004, retrospective observational study. SETTING & PARTICIPANTS: 189,773 candidates listed for kidney-only transplant; 93,604 kidneys transplanted, 15,580 kidneys discarded. PREDICTOR: Blood type and demographic/clinical variables. OUTCOMES & MEASUREMENTS: The extent of disparities in waiting times and concurrent differences in recovery, discard, live donor, and deceased donor transplant rates. RESULTS: Blood type O, A, B, and AB candidates constituted 48%, 34%, 14%, and 4% of the list, respectively. Live donor transplant rates were lowest for type AB candidates (13.4% vs 15.5%, 16.8%, and 15.2%; P < 0.001). On multivariate analysis, type AB candidates had a 1.5-fold greater chance of receiving deceased donor kidney transplants than blood group A candidates (95% CI, 1.45-1.55). Recovery rates of type AB kidneys were similar to those for other blood types, whereas discard rates of type AB kidneys were significantly higher (adjusted OR [aOR], 1.71; 95% CI, 1.56-1.89) for both expanded criteria (aOR, 1.78; 95% CI, 1.52-2.09) and standard criteria donors (aOR, 1.67; 95% CI, 1.48-1.89). LIMITATIONS: Observational data. Potential confounding from unmeasured covariates. CONCLUSION: Allocation of type A kidneys to type AB recipients not only increases disparities in waiting times between these 2 groups; but concurrent with the shorter waiting times for type AB candidates, there is suboptimal use of type AB deceased donor and living donor kidneys.10a*Tissue Donors10aABO Blood-Group System / *blood10aAdolescent10aAdult10aAged10aCohort Studies10aFemale10aFollow-Up Studies10aHumans10aKidney / metabolism10aKidney Transplantation / *methods / *utilization10aMale10aMiddle Aged10aRetrospective Studies10aTissue and Organ Procurement / *methods / *utilization10aYoung Adult1 aKayler, L K1 aSegev, D L  uhttps://www.notifylibrary.org/reference/779