01971nas a2200217   4500008003900000245011600039210006900155260000800224300001400232490000700246520132200253100001901575700001501594700002001609700001801629700001501647700001201662700001501674700001601689856004801705       2005                          d00aPelvic magnetic resonance imaging after bone marrow harvest a retrospective study in 50 unrelated marrow donors0 aPelvic magnetic resonance imaging after bone marrow harvest a re  cApr  a667 - 6730 v353 aA total of 50 unrelated marrow donors were examined by pelvic magnetic resonance imaging (MRI) to investigate the morphological sequelae of bone marrow harvesting (BMH). Signal increase in T2-weighted sequences and contrast media enhancement in T1 sequences at the operative sites were found as typical MRI morphology 4 weeks after harvest (group A, n = 16), corresponding to edema, hyperemia and proliferative activity. Although tissue repair was completed in the majority of donors 1 year after BMH, about 36% of donors in group B (n = 16) had abnormal findings. These included a persistence of the 'acute injury' signal pattern (2/16, 12%), and signal alterations due to fatty marrow conversion (4/16, 24%). The proportion of MRI abnormalities increased to over 70% in two-time donors ( group C, n = 11), which might indicate a cumulation of tissue damage after repetitive harvests. If donors had experienced prolonged discomfort after BMH (group D, n = 7), MRI revealed pathological signals in 86%. In conclusion, the MRI morphology reflects the pathophysiological reactions after BMH, including inflammation and tissue repair. A further prospective evaluation in a larger number of donors is necessary to confirm these results and to identify the factors which influence the extent and duration of tissue damage.1 aKroschinsky, F1 aKittner, T1 aMauersberger, S1 aRautenberg, U1 aSchuler, U1 aRutt, C1 aLaniado, M1 aEhninger, G  uhttps://www.notifylibrary.org/reference/839