08135nas a2200181   4500008004500000022001400045245006400059210006000123260001000183300000700193490000700200520761200207653002307819100002107842700002107863700002007884856004907904       2005                        Engldsh    a1527-646500aThe development of food allergy after liver transplantation0 adevelopment of food allergy after liver transplantation  cMarch  a260 v113 a: The acquisition of new food allergy after orthotopic liver transplantation is now a well described phenomenon, mainly reported in children. The etiology of this phenomenon is at present unclear, but has been ascribed by some to tacrolimus treatment. Here we report a case of liver transplant acquired food allergy (LTAFA) in a child who received a split liver graft. The case is remarkable for the absence of new food allergy in the adult recipient of the same graft. This suggests that host-specific factors play an important role in the development of food allergy after liver transplantation, and emphasizes the predisposition that children have toward this phenomenon. Possible mechanisms underlying the development of food allergy after liver transplantation are discussed. In conclusion, tacrolimus treatment alone cannot account for LTAFA. Host factors such as the maturity of immune regulatory mechanisms are likely to play a critical role in the development of new food allergy after a liver transplant. (Liver Transpl 2005;11:326-330.) Copyright (C) 2005 John Wiley & Sons, Inc.; References: 1. Legendre C, Caillat-Zucman S, Samuel D, Morelon S, Bismuth H, Bach JF, et al. Transfer of symptomatic peanut allergy to the recipient of a combined liver-and-kidney transplant. N Engl J Med 1997; 337: 822-824. 2. Phan TG, Strasser SI, Koorey D, McCaughan GW, Rimmer J, Dunckley H, et al. Passive transfer of nut allergy after liver transplantation. 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