02091nas a2200241   4500008004100000020001400041024001700055245012600072210006900198260021600267300001400483490000700497520112800504653003001632653002701662653001501689100001801704700001601722700001901738700002001757700002301777856004901800       2005                        eng d  a0902-0063  abb5, 871024000aSafety of using hepatitis B virus core antibody or surface antigen-positive donors in kidney or pancreas transplantation.0 aSafety of using hepatitis B virus core antibody or surface antig  aCopyright (C) 2005 Blackwell Publishing Ltd.b(a)Nephrology, Mount Sinai School of Medicine, New York, NY, USA(b)Recanati/Miller Transplantation Institute, Mount Sinai School of Medicine, New York, NY, USAc2005  a364 - 3660 v193 aHepatitis B virus core antibody (HBcAb) or surface antigen (HBsAg)-positive organ donors have the potential to transmit infection to transplant recipients. We investigated the safety of using HBcAb(+) or HBsAg(+) donors in kidney or pancreas transplant recipients with 1 yr lamivudine prophylaxis. While HBsAb(-) recipients of HBcAb(+) donors received prophylaxis, HBsAb(+) recipients did not. HBsAg(+) organs were only used in patients who were both HBcAb and HBsAb(+). Forty-six patients received HBcAb(+) and four received HBsAg(+) organs (47 kidney, two pancreas, and one kidney/pancreas). All but one recipient were HBsAg(-), 25 were HBsAb(+), and 19 HBcAb(+). During a median 36 months of follow-up (range 6-66 months), with 43 of a total 50 patients having at least 1 yr follow-up and were off lamivudine, and none of the patients developed hepatitis B viremia or seroconversion to HBsAg or HBsAb(+). These results suggest that HBcAb(+) or HBsAg(+) organs can be used safely in selected recipients with lamivudine prophylaxis without requiring hepatitis B immunglobulin., Copyright (C) 2005 Blackwell Publishing Ltd.10ahepatitis B core antibody10aKidney Transplantation10alamivudine1 aAkalin, Enver1 aAmes, Scott1 aSehgal, Vinita1 aMurphy, Barbara1 aBromberg, Jonathan  uhttps://www.notifylibrary.org/reference/4303