02635nas a2200181   4500008004100000020001400041245012900055210006900184260018200253300001400435490000700449520187000456100001502326700001802341700002202359700002302381856004902404       2013                        eng d  a1527-646500aIncidence of death and potentially life-threatening near-miss events in living donor hepatic lobectomy: A world-wide survey.0 aIncidence of death and potentially lifethreatening nearmiss even  aCopyright (C) 2013 John Wiley & Sons, Inc.b(1) Department of Transplantation and Hepatobiliary Diseases, Lahey Clinic Medical Center, Tufts Medical School, Burlington, MAc2013  a499 - 5060 v193 a: The incidence of morbidity and mortality after living donor liver transplantation (LDLT) is not well understood because reporting is not standardized and relies on single-center reports. Aborted hepatectomies (AHs) and potentially life-threatening near-miss events (during which a donor's life may be in danger but after which there are no long-term sequelae) are rarely reported. We conducted a worldwide survey of programs performing LDLT to determine the incidence of these events. A survey instrument was sent to 148 programs performing LDLT. The programs were asked to provide donor demographics, case volumes, and information about graft types, operative morbidity and mortality, near-miss events, and AHs. Seventy-one programs (48%), which performed donor hepatectomy 11,553 times and represented 21 countries, completed the survey. The average donor morbidity rate was 24%, with 5 donors (0.04%) requiring transplantation. The donor mortality rate was 0.2% (23/11,553), with the majority of deaths occurring within 60 days, and all but 4 deaths were related to the donation surgery. The incidences of near-miss events and AH were 1.1% and 1.2%, respectively. Program experience did not affect the incidence of donor morbidity or mortality, but near-miss events and AH were more likely in low-volume programs (<=50 LDLT procedures). In conclusion, it appears that independently of program experience, there is a consistent donor mortality rate of 0.2% associated with LDLT donor procedures, yet increased experience is associated with lower rates of AH and near-miss events. Potentially life-threatening near-miss events and AH are underappreciated complications that must be discussed as part of the informed consent process with any potential living liver donor. Liver Transpl 19:499-506, 2013. (C) 2012 AASLD., Copyright (C) 2013 John Wiley & Sons, Inc.1 aCheah, Yee1 aSimpson, Mary1 aPomposelli, James1 aPomfret, Elizabeth  uhttps://www.notifylibrary.org/reference/4447