TY - JOUR T1 - Visceral leishmaniasis after orthotopic liver transplantation: impact of persistent splenomegaly. JF - Transplant international : official journal of the European Society for Organ Transplantation//Transpl Int Y1 - 1993 A1 - Horber, F F A1 - Lerut, J P A1 - Reichen, J A1 - Zimmermann, A A1 - Jaeger, P A1 - Malinverni, R KW - *Leishmaniasis, Visceral/et [Etiology] KW - *Liver Diseases, Parasitic/et [Etiology] KW - *Liver Transplantation/ae [Adverse Effects] KW - Female KW - Humans KW - Leishmaniasis, Visceral/pa [Pathology] KW - Liver Diseases, Parasitic/pa [Pathology] KW - Liver Transplantation/pa [Pathology] KW - Middle Aged AB - Visceral leishmaniasis was observed in a 50-year-old female liver transplant recipient 1 year following transplantation. Signs of active infection were low-grade fever, pancytopenia, persistent splenomegaly, positive cultures for leishmania in liver and bone marrow biopsy specimens, and newly positive leishmania serology. Following sequential therapy with pentavalent antimony and amphotericin B, blood values improved massively, bone marrow cultures became negative, and leishmania serology decreased. Secondary prophylaxis with fluconazole was instituted and the patient remains without signs of active infection 1 year after successful therapy. M1 - ady, 8908516 PB - Horber,F F. Medizinische Universitatspoliklinik, Inselspital, Bern, Switzerland. CY - GERMANY VL - 6 SN - 0934-0874 CP - 1 L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=med3&NEWS=N&AN=8452634 ID - 4337 ER -