TY - JOUR T1 - A delayed hemolytic transfusion reaction (DHTR) with multiple alloantibodies (Anti-E, Jka, Dia, Fyb, and S) induced by E-antigen-negative, crossmatch-compatible blood. JF - Immunopharmacology and immunotoxicology//Immunopharmacol Immunotoxicol Y1 - 1998 A1 - Yamane, K A1 - Yagihashi, A A1 - Sasaki, M A1 - Kuwashima, K A1 - Morio, A A1 - Watanabe, N KW - *Blood Group Incompatibility/im [Immunology] KW - *Erythrocyte Transfusion/ae [Adverse Effects] KW - *Hemolysis/im [Immunology] KW - *Hepatitis B e Antigens/im [Immunology] KW - *Isoantibodies/bi [Biosynthesis] KW - *Isoantibodies/im [Immunology] KW - *Kidd Blood-Group System/im [Immunology] KW - Adult KW - Blood Grouping and Crossmatching KW - Erythrocytes/im [Immunology] KW - Female KW - Hepatitis B e Antigens/bl [Blood] KW - Humans KW - Isoantibodies/bl [Blood] AB - We describe the case of a 44-year-old woman with a delayed hemolytic transfusion reaction (DHTR). She had a history of two pregnancies and a blood transfusion, the details of which were unknown. At the time of her first vascular surgery on November 15, 1989, she received 1200 ml of crossmatch-compatible concentrated red blood cells (CRC). Before the first operation, screening for anti-RBC antibodies (Ab) was negative. At the time of the second admission on Feburary 15, 1996, anti-E Abs were detected by indirect antiglobulin test. She received 560 ml of E-antigen-negative, crossmatch-compatible, CRC for treatment of anemia on March 1 and 2, 1996. After this transfusion, total bilirubin (1.6 mg/dl) and lactate dehydrogenase (1355 IU/ml) were elevated on March 12, 1996. She had no evidence of clinical hemolysis. We suspected DHTR from these data, and therefore screened for anti-RBC Abs. Anti-E, Jka, Dia, Fyb, and S Abs were detected in blood samples obtained from the patient on March 12, 1996. Anti-E, Jka Dia, and S Abs were present more than 1 month and anti-Fyb Ab was disappeared at 18 days after transfusion. M1 - iai, 8800150 PB - Yamane,K. Department of Laboratory Diagnosis, Sapporo Medical University School of Medicine, Japan. CY - UNITED STATES VL - 20 SN - 0892-3973 CP - 4 L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=med4&NEWS=N&AN=9805232 ID - 4442 ER -