Welcome to the NOTIFY Library site where experts from across the globe collaborate to share didactic information on documented adverse outcomes associated with the application of human organs, blood, tissues and cells. We aim to support continued improvements in safety and efficacy in transplantation, transfusion and assisted reproduction. The data presented on the Notify Library site should be seen in the context of impressive success stories in transplantation and assisted reproduction across the world.

  • Notify Library: Website Visits




    In this section it is possible to visualize the total visits from 2012 to date divided by year.

  • The NOTIFY Booklet


    The NOTIFY booklet  aims to provide a didactic overview of Vigilance and Surveillance for Medical Products of Human Origin (MPHO) targeting clinicians and health authorities. This guidance provides examples which demonstrate the improvement of the care of both the recipients and donors, from the recognition and diagnosis of adverse reactions to the appropriate investigations and treatment after having drawn upon the references in the NOTIFY Library.

  • World Health Assembly Executive Board Acknowledges Exceptional Nature of MPHO


    At the 136th meeting of the WHA Executive Board (EB) in January 2015, a proposal from Italy, Lithuania, Malta, Slovenia and Spain to work towards consensus on the principles for the donation and management of blood and other Medical Products of Human Origin (MPHO) was DOCUMENTED. The discussion was based on a REPORT submitted to the EB for possible future consideration by the full WHA. This important initiative raises the acknowledgement of the exceptional nature of MPHO

  • WHO Technical Meeting for the NOTIFY Library Barcelona 23-25 February 2015


    The first technical meeting of the NOTIFY Library Editorial Groups was held in collaboration with the Spanish National Transplantation Organization (ONT) and hosted by the Catalan Organization of Transplantation (OCATT). The groups worked on new cases for the library, piloting a newly developed online tool for case submission and review. A separate technical commission elaborated new proposals for promoting vigilance and surveillance of MPHO, utilizing the library’s resources and its global expertise.

  • NOTIFY: Exploring Vigilance Notification for Organs, Tissues and Cells


    The document presents the results of the NOTIFY Bologna Initiative, a meeting of 113 invited experts from 36 countries that took place in Bologna from February 7th to 9th 2011 to consider and discuss the didactic value of documented adverse occurrences (click here to download the full report). At this meeting, the idea of an open-access searchable database of adverse occurrences in this field globally was conceived and the Italian National Transplant Centre accepted the task of creating the NOTIFY library collaborating with global experts.

The NOTIFY search engine is accessible without username and password.

The database is continually updated and currently new cases are being collected and submitted to editorial working groups in order to increase the database content and scope. Following the last WHO Consultation meeting in Brasìlia in December 2013, new international experts were asked to collaborate in the existing editorial working groups,including a new group of hemovigilance experts for the incorporation of Transfusion Reactions in the database.