Acute Hemolytic Transfusion Reaction (AHTR), anti-c

Status:

Ready to upload

Record number:

1267

Adverse Occurrence type:

Acute Hemolytic Reaction

MPHO Type:

Red blood cells

Estimated frequency:

Case report

Time to detection:

minutes

Alerting signals, symptoms, evidence of occurrence:

Fever, chills, dyspnea, bilateral loin pain.

Demonstration of imputability or root cause:

Clinical and serology results, hemoglobinuria.

Imputability grade:

2 Probable

Groups audience:

Clinical complications

Keywords:

AHTR (acute hemolytic transfusion reaction)

RBC (red blood cell)

IAT (indirect antiglobulin test )

References:

Acute intravascular haemolytic transfusion reaction due to anti-c undetected by conventional pretransfusion cross-matching tests.

Reference attachment:

* AHTR anti-c, Pradhan, 1999.pdf

Suggest references:

Pradhan, D. and Chaudhary, R. (1999). Acute intravascular haemolytic transfusion reaction due to anti-c undetected by conventional pretransfusion cross-matching tests. Am J Hematol 61(1):82-83

Expert comments for publication:

A striking finding was the discordancy between strongly positive antibody screen using polyethylene glycol antiglobulin test (PEG-AGT) but not with saline or enzyme treated crossmatches.