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VIDEO TUTORIAL
Database content analysis
Notify Booklet
1 INTRODUCTION
2 THE V&S CHAIN FOR MPHOs
3 VIGILANCE AND SURVEILLANCE: HISTORY AND BASIC ELEMENTS
4 MEDICAL PRODUCTS OF HUMAN ORIGIN (MPHO) - DONATION AND ETHICS
ANNEX 1. Notify Library - MPHO type taxonomy
5 TOWARDS A GLOBAL GOVERNANCE OF MPHO
6 THE V&S SYSTEM IS PRIMARILY A RESPONSIBILITY FOR HEALTH AUTHORITIES
7 ORGANIZATION FOR A COMPREHENSIVE - VIGILANCE & SURVEILLANCE SYSTEM
8 VIGILANCE & SURVEILLANCE - RECOGNITION RELIES ON HEALTH CARE STAFF
9 INVESTIGATING OCCURRENCES THAT COULD CAUSE HARM - LEARNING FROM ERRORS
10 PROJECT NOTIFY
11 THE NOTIFY DATABASE - LEARNING FROM VIGILANCE
12 RISKS ASSOCIATED WITH LIVING DONATION
13 HARM TO RECIPIENT - INFECTIONS
14 HARM TO RECIPIENT - NON INFECTIOUS BLOOD TRANSFUSION REACTIONS
15 HARM TO RECIPIENTS - MALIGNANCY
16 HARM TO RECIPIENTS - GENETIC TRANSMISSIONS - HPC
17 HARM TO RECIPIENTS - GENETIC TRANSMISSIONS - gamets and embryos
18 CHARACTERISTICS, HANDLING AND CLINICAL ERRORS
19 TRACEABILITY, AN ABSOLUTE PRE-REQUISITE FOR MPHO SAFETY
ANNEX 2. Notify Library - Adverse occurrence type taxonomy
REFERENCES
Background Documents
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Adverse occurrence type
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Harm to a Recipient
Infection
Bacterial
Acinetobacter
Alcaligenes
Anaplasma
Bacillus
Bacteroides
Bartonella
Brucella
Cardiobacterium
Chlamydia
Citrobacter
Clostridium
Ehrlichia
Elizabethkingia
Enterobacter
Enterococcus
Escherichia
Francisella
Hafnia
Klebsiella
Legionella
Listeria
Morganella
Mycobacterium
Mycoplasma
Oerskovia
Orientia
Prevotella
Propionibacterium
Proteus
Providencia
Pseudomonas
Psychrobacter
Rickettsia
Salmonella
Serratia
Staphylococcus
Stenotrophomonas
Streptococcus
Treponema
Ureaplasma
Veillonella
Yersinia
Fungal
Acremonium
Apophysomyces
Arthrographis
Aspergillus
Candida
Coccidioides
Cryptococcus
Histoplasma
Encephalitozoon
Paecilomyces
Rhodotorula
Scedosporium
Sporothrix
Talaromyces
Parasitic
Acanthamoeba
Babesia
Balamuthia
Clonorchis
Echinococcus
Halicephalobus
Leishmania
Plasmodium
Schistosoma
Strongyloides
Toxoplasma
Trypanosoma
Wuchereria
Prion
CJD
vCJD
Viral
Adenovirus
Arenavirus
BK virus (BKV)
Borna disease virus (BDV)
Colorado tick fever virus
Cytomegalovirus (CMV)
Dengue (DENV)
Eastern Equine Encephalitis Virus (EEEV)
Enterovirus
Epstein-Barr Virus (EBV)
Hepatatis A Virus (HAV)
Hepatitis B Virus (HBV)
Hepatitis C Virus (HCV)
Hepatitis E virus (HEV)
Herpes simplex Virus (HSV)
Human Herpes Virus 6 (HHV-6)
Human Herpes Virus 8 (HHV-8)
Human immunodeficiency virus (HIV)
Human papillomavirus (HPV)
Human T-lymphotropic Virus (HTLV)
Influenza virus
Japanese encephalitis virus (JEV)
JC virus
Lymphocytic choriomeningitis virus (LCMV)
Parvovirus B19
Rabies virus
Ross River virus (RRV)
Saint Louis encephalitis virus (SLEV)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Tick-borne encephalitis virus (TBEV)
West Nile Virus (WNV)
ZIKA Virus (ZIKV)
Type not specified
Malignancy
Blood and lymphoid
Leukemia, lymphocytic, acute lymphoblastic
Leukemia, lymphocytic, chronic
Leukemia, monocytic, acute
Leukemia, myeloid, acute myelogenous (includes myeloid sarcoma)
Leukemia, myeloid, promyelocytic
Leukemia, type not specified
Lymphoma, B-cell, diffuse large type
Lymphoma, B-cell, other or not further specified
Lymphoma, T cell
Lymphoma, type not specified
MGUS (monoclonal gammopathy of unknown significance)
Multiple myeloma/plasmacytoma leukemia
Myelodysplastic syndrome
Breast
Breast cancer, other or type not specified
Lobular adenocarcinoma
Carcinoma of unknown primary site
Cancer, multiple types
Central nervous system
Astrocytoma (WHO grade 3)
Astrocytoma/glioblastoma multiforme (WHO grade 4)
Astrocytomas and glioblastomas not further specified (WHO grade 1-4)
CNS lymphoma
CNS tumor, other or type not specified
Malignant Meningioma (WHO grade 3)
Medulloblastoma (WHO grade 4)
Gastrointestinal
Colorectal adenocarcinoma
Other or type not specified
Small bowel adenocarcinoma
Germ cell, sex cord and related tumors
Choriocarcinoma
Germ cell tumor, other or type not specified
Head and neck
Squamous cell carcinoma, larynx and hypopharynx
Kidney and urinary tract
Angiomyolipoma
Renal cancer, other or type not specified
Renal cell carcinoma
Urothelial (transitional) cell carcinoma
Liver, gallbladder and bile ducts
Cholangiocarcinoma
Hepatocellular carcinoma
Liver cancer, other or type not specified
Lung and lower respiratory system
Lung cancer, adenocarcinoma
Lung cancer, small cell and other neuroendocrine tumors
Lung cancer, squamous cell (bronchogenic)
Lung cancer, other or type not specified
Neuroendocrine tumors
Neuroendocrine carcinoma
Paraganglioma, pheochromocytoma
Small cell carcinoma
Ovaries and fallopian tubes
Ovaries and fallopian tubes, other or type not specified
Pancreas
Pancreatic (ductal) adenocarcinoma
Prostate
Prostate adenocarcinoma/carcinoma
Skin
Melanoma
Skin cancer, other or type not specified
Soft tissue/sarcoma
Angiosarcoma
Kaposi's sarcoma
Nerve sheath tumor NOS
Sarcoma, other or type not specified
Thyroid
Papillary carcinoma
Thyroid cancer, other or type not specified
Non-infectious, Non-malignant transmissions
Alloimmune
Autoimmune
Genetic
Hypersensitivity, Allergy
Immunological complications
Acute Hemolytic Reaction
Allergic Reaction
Delayed Hemolytic Reaction
Delayed Serologic Reaction
Detrimental immunization
ABO immunisation
HLA immunisation
Rh immunisation
Other
Graft versus host disease
Passive alloimmune thrombocytopenia
Post Transfusion Purpura (PTP)
Rejection
Transfusion Related Lung Injury (TRALI)
Miscellaneous complications
Cardiovascular
Catheter related complications
Delayed engraftment
Febrile reaction
Graft failure
Hypotensive Reaction
Neurological
Pulmonary
Surgical site
Transfusion-Associated Circulatory Overload (TACO)
Transfusion-Associated Dyspnea (TAD)
Toxicity
Chemiotherapy drugs
Citrate
DMSO
Ethylene oxide
Undue exposure to risk-intervention
Other
Harm to a Donor
Allergic reaction
Local
Drug related reactions
GCSF-related
Ovarian Hyperstimulation Syndrome
Embolic complications
Air embolism
Fat embolism
Thromboembolism
Excessive collection/removal
Infection
Malignancy
Miscellaneous complications
Anesthetic agents
Cardiovascular
Catheterization/Intubation
Gastrointestinal
Immunological
Insertion of needle
Metabolic
Neurological
Psychological
Pulmonary
Surgical site
Toxicity
Citrate
Vasovagal reactions
Other
Harm to a Fetus or Offspring
Genetic
Risk of harm
Donor disease without transmission
Loss
Highly matched or autologous MPHO
Large quantity of unmatched MPHO
Suitable organ(s)
Mix-up
Embryo
Gamete
Incorrect MPHO applied - no harm
Unsuitable MPHO released for clinical use - no harm
Other
Medical Products of Human Origin type - MPHO
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Organs
Heart
Kidney
Liver
Lung
Pancreas
Small bowel
Combined
Heart Lung
Kidney Pancreas
Liver Kidney
Liver Small bowel
Multivisceral
Composite tissues grafts
Face
Hand
Uterus
Multiple types or not specified
Blood
Granulocytes
Plasma
Platelets
Red blood cells
Whole blood
Type not specified
Cells
Chondrocytes
Dendritic cells
HPC
Apheresis
Cord Blood
Marrow
Type not specified
Mesenchymal stem cells
Olfactory mucosal cells
Pancreatic Islets
T-lymphocytes
Tissues
Adipose tissue
Amniotic Membrane
Cardiovascular
Blood vessels
Pericardium
Heart valves
Dura mater
Musculoskeletal
Bone
Meniscus
Osteochondral
Tendon or Ligament
Nerve
Ocular
Cornea
Limbal tissue
Sclera
Skin
Reproductive
Embryo
Oocyte
Ovarian tissue
Sperm
Combined
MPHO-Derived medicinal products
Plasma derivates
Other
Milk
Topical products of human origin
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2020
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2005
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2003
2002
2001
2000
1999
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1996
1995
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1990
1989
1988
1987
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1982
1981
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