Status:
Ready to upload
Record number:
1487
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
Retrospective cohort study at Mayo Clinic 1.3 -1.4% of non-cardiac surgery transfused patients
Time to detection:
<6 hours
Alerting signals, symptoms, evidence of occurrence:
2004 Canadian consensus conference criteria
Demonstration of imputability or root cause:
TRALI and Possible TRALI criteria; records reviewed rather than relying on passive reporting (which provided no reported cases)
Imputability grade:
2 Probable
Groups audience:
Keywords:
Suggest new keywords:
antibodies
Reference attachment:
Suggest references:
Clifford, L., Jia, W., Subramanian, A., Tadav, H., Wilson, G.A., Murphy, S.P., Pathak, J. Schroeder, D. R. and Kor, D.J. (2015). Characterizing the Epidemiology of Postoperative Transfusion-related Acute Lung Injury. Anesthesiology 122(1):12-20
Expert comments for publication:
0/45 TRALI or possible TRALI cases were reported to the transfusion service. Perioperative TRALI/possible TRALI is more common than previously reported and its risk increases with greater volumes of blood component therapies.