Pulmonary Embolism

Status:

Ready to upload

Record number:

1669

Adverse Occurrence type:

Thromboembolism

MPHO Type:

Whole blood

Estimated frequency:

Rare

Time to detection:

Immediate

Alerting signals, symptoms, evidence of occurrence:

Donor became short of breath immediately after donation, dizzy, with severe shortness of breath within 12 hours. Ventilation/Perfusion (V/Q) scan showed bilateral small peripheral embolisms in the lungs.

Demonstration of imputability or root cause:

Positive V/Q scan.

Imputability grade:

3 Definite/Certain/Proven

Groups audience:

Keywords:

VQ scan (ventilation-perfusion scan)

oral contraceptives

healthy donor

References:

Pulmonary embolism after blood donation in a healthy young female.

Suggest new keywords:

Pulmonary embolism

Reference attachment:

PE Brtitish Blood Transfusio.pdf

Suggest references:

Basu M, Georgsen J, Assing K. (2015). Pulmonary embolism after blood donation in a healthy young female. Transfusion Medicine

Expert comments for publication:

The donor was a healthy 18 year old female, previous blood donor. Venipuncture was atraumatic. She had no family or genetic predisposition to thrombophilia. She was a non-smoker. Laboratory workup showed normal levels of antithrombin, cardiolipin antibodies, protein C and S and no specific Factor V Leiden or Factor 2 gene mutations. Her only risk factor was use of third generation combined oral contraceptives.