Registry series: Acute Lymphocyte Leukemia (ALL) (1982)

Record number:

238

Adverse Occurrence type:

Leukemia, lymphocytic, acute lymphoblastic

MPHO Type:

Estimated frequency:

3/243; 3/10489; - Most recent risk assessment for leukemia, lymphoma and plasmacytoma (Council of Europe, 2025): Leukaemia, lymphoma and plasmacytoma diagnosed during donor procurement: These cancers are classified as an unacceptable risk for organ donation. Leukaemia, lymphoma and plasmacytoma in the donor history: Active (acute or chronic) leukaemia, lymphoma and plasmacytoma are an unacceptable risk for organ donation. Treated acute leukaemia and lymphoma after a definite disease-free interval of 10 years may be considered for organ donation with an assumed high risk for transmission.

Time to detection:

17 (4-164) months

Alerting signals, symptoms, evidence of occurrence:

Elevated white blood cell count; thrombopenia; anemia;

Demonstration of imputability or root cause:

Cytogenetics in donor cells; additional aberrations in host cells; cytogenetics and molecular markers

Keywords:

cytogenetics

ALL (acute lymphoblastic leukemia)

elevated white blood cell count

malignancy

allogeneic