Record number:
243
Adverse Occurrence type:
MPHO Type:
Time to detection:
15 months
Alerting signals, symptoms, evidence of occurrence:
At time of transplant, routine liver biopsy of donor showed adenocarcinoma of unknown primary site; heart had already been transplanted. Metastatic spine lesion in heart recipient identified at 15 months, biopsy compatible with adenocarcinoma.
Demonstration of imputability or root cause:
Assessment of disease transmission studied by biopsy confirmatory with comparison of the recipient cancer to the primary donor tumour or in some cases genetic allelic analysis (not specified in this particular case).
Imputability grade:
3 Definite/Certain/Proven
Groups audience:
Suggest new keywords:
heart transplant
deceased donor
Registry series
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Expert comments for publication:
This is one case in a series of cases in this report from the Penn Registry.