| Title | Immune hemolysis after an ABO mismatched renal transplant |
| Publication Type | Journal Article |
| Year of Publication | 1989 |
| Authors | Perkins AC, Richards VL, Gibson J, Joshua DE, Johnson JR, Kronenberg H |
| Journal | Aust N Z J Med |
| Volume | 19 |
| Issue | 4 |
| Pagination | 345 - 6 |
| Date Published | Aug |
| ISSN | 0004-8291 (Print) 0004-8291 (Linking) |
| Accession Number | 2675813 |
| Keywords | *Kidney Transplantation, ABO Blood-Group System / *immunology, Adult, Anemia, Hemolytic, Autoimmune / *etiology / immunology, Autoantibodies / analysis, Cyclosporins / adverse effects / immunology, Graft Survival / drug effects, Humans, Male |
| Abstract | We describe a case of immune hemolysis due to anti-B occurring in a blood group B patient 16 days after a cadaveric renal transplantation from a blood group O donor. Transfusional support was initially required and the direct antiglobulin test (DAT) remained positive for 80 days. Cyclosporin A (CSA), which was used for rejection prophylaxis in this case, has unique immunosuppressive capabilities which protects transplanted organs from rejection, but which might permit this type of 'graft versus host' reaction. |
| Notify Library Reference ID | 1265 |
