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Home / Harm to a Donor / Drug related reactions / GCSF-related / Leukopenia

Leukopenia

Record number: 
517
Adverse Occurrence type: 
GCSF-related
MPHO Type: 
Apheresis
Estimated frequency: 
Common
Time to detection: 
During injections or apheresis
Alerting signals, symptoms, evidence of occurrence: 
Leukopenia
Demonstration of imputability or root cause: 
Definite/probable
Keywords: 
leukopenia
G-CSF (granulocyte colony-stimulating factor)
PBSC (peripheral blood stem cells)
apheresis
donor reaction
allogeneic
References: 
Adverse events among 2408 unrelated donors of peripheral blood stem cells: results of a prospective trial from the National Marrow Donor Program
Peripheral blood stem cell mobilization and apheresis: analysis of adverse events in 94 normal donors
Sustained decrease of peripheral lymphocytes after allogeneic blood stem cell aphereses
Recovery and safety profiles of marrow and PBSC donors: experience of the National Marrow Donor Program.
Short- and long-term haematological surveillance of healthy donors of allogeneic peripheral haematopoietic progenitors mobilized with G-CSF: a single institution prospective study
Donation of stem cells from blood or bone marrow: results of a randomised study of safety and complaints
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The cases, bibliography and associated comments included in this website and database have been provided by experts worldwide and reviewed by voluntary editorial working groups. The data and information is not guaranteed to be complete or to be fully up to date at any particular moment and it reflects the knowledge and views of the experts participating, not those of the World Health Organisation or the Italian National Transplant Centre.