Transmission of malignancy with solid organ transplants

TitleTransmission of malignancy with solid organ transplants
Publication TypeJournal Article
Year of Publication2005
AuthorsMorath C, Schwenger V, Schmidt J, Zeier M
Issue1 Suppl
PaginationS164 - 6
Date PublishedSep 27
Accession Number16286898
Keywords*Neoplasms / epidemiology, Central Nervous System Neoplasms / epidemiology, Humans, Postoperative Complications / epidemiology / prevention & control, Tissue Donors / *statistics & numerical data

Donor-derived malignancy is found in about 0.02-0.2% of allograft recipients. With an increasing number of older donors, this problem will gain more relevance in the future. We wish to review the current literature on tumor transmission with solid organ transplants and focus on the consequences of an extension of the donor pool, such as by the use of donors with a history of cancer. Finally, suggestions are made for screening regimens for living as well as cadaveric donors to minimize the risk of inadvertent tumor transmission.

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