Balamuthia mandrillaris meningoencephalitis: survival of a pediatric patient

TitleBalamuthia mandrillaris meningoencephalitis: survival of a pediatric patient
Publication TypeJournal Article
Year of Publication2010
AuthorsCary LC, Maul E, Potter C, Wong P, Nelson PT, Given, C. 2n, Robertson W.
Paginatione699 - 703
Date PublishedMar
ISSN1098-4275 (Electronic) 0031-4005 (Linking)
Accession Number20123772
Keywords*Amebiasis, *Amoebozoa, Child, Preschool, Humans, Male, Meningoencephalitis / *parasitology, Survivors

Balamuthia mandrillaris infections are rare and almost always fatal. This ameba is a naturally occurring soil inhabitant that can cause disease in immunocompetent hosts, with early diagnosis typically proving difficult. We recently cared for a previously healthy 2-year-old boy who was diagnosed with meningoencephalitis secondary to B mandrillaris relatively early in his presentation, which enabled us to initiate targeted antimicrobial therapy. Since discharge from the hospital the child has shown slow, steady improvement with dramatic improvements seen on follow-up brain imaging. Our observations suggest that early diagnosis and treatment may significantly reduce mortality and morbidity rates from this highly virulent organism.

Notify Library Reference ID300

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