Laboratory Identification of Donor-Derived Coxsackievirus B3 Transmission.

TitleLaboratory Identification of Donor-Derived Coxsackievirus B3 Transmission.
Publication TypeJournal Article
Year of Publication2015
AuthorsAbbott I., Papadakis G., Kaye M., Opdam H., Hutton H., Angus P., Johnson P., Kanellis J., Westall G., Druce J., Catton M.
Journal//Am J Transplant
Volume15
Issue2
Pagination555 - 559
Date Published2015
ISBN Number1600-6135
Other Numbers100968638
Keywordsclinical research/practice, donors and donation: donor-derived infections, infection and infectious agents, infectious disease, Viral
Abstract

: Unexpected donor-to-recipient infectious disease transmission is an important, albeit rare, complication of solid organ transplantation. Greater work and understanding about the epidemiology of these donor-derived transmissions is continually required to further mitigate this risk. Herein we present the first reported case of proven donor-derived transmission of coxsackievirus serogroup-3, an enterovirus, following solid organ transplant. Swift and effective communication between the organ donation agency, treating physicians, laboratory testing and notification ensured a coordinated approach. The resulting clinical syndromes in the organ recipients were mild. This case highlights the requirement for ongoing surveillance over a broad range of infecting pathogens that may present as a donor-derived infection., The authors describe the first reported case of proven donor-derived transmission of coxsackievirus serogroup-3, an enterovirus, following solid organ transplant., (C) 2015 John Wiley & Sons, Ltd

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