Herpes simplex hepatitis after liver transplantation: case report and literature review.

TitleHerpes simplex hepatitis after liver transplantation: case report and literature review.
Publication TypeJournal Article
Year of Publication2014
AuthorsCote-Daigneault J, Carrier FM, Toledano K, Wartelle-Bladu C, Willems B
JournalTransplant infectious disease : an official journal of the Transplantation Society// Transpl Infect Dis
Volume16
Issue1
Pagination130 - 4
Date Published2014//
ISBN Number1399-3062
Other Numbersd1d, 100883688
Keywords*Encephalitis, Herpes Simplex/tm [Transmission], *Hepatitis, Viral, Human/tm [Transmission], *Herpes Simplex/tm [Transmission], *Herpesvirus 1, Human, *Liver Transplantation/ae [Adverse Effects], *Transplants/vi [Virology], Acyclovir/tu [Therapeutic Use], Antiviral Agents/tu [Therapeutic Use], Encephalitis, Herpes Simplex/dt [Drug Therapy], Fatal Outcome, Hepatitis, Viral, Human/dt [Drug Therapy], Hepatitis, Viral, Human/et [Etiology], Herpes Simplex/dt [Drug Therapy], Humans, Liver Failure, Acute/et [Etiology], Male, Middle Aged
Abstract

Herpes simplex virus (HSV) hepatitis is an uncommon cause of liver failure, but may have a dramatic outcome. We herein present a case report of a liver graft infection by HSV-1 associated with liver failure and encephalitis. A complete hospital chart review of the case and a literature search were undertaken. Literature review suggests that herpes simplex acute liver failure is rare and associated with a poor prognosis, even with early treatment. Novel diagnostic and preventive approaches need to be instituted. Copyright © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
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