| Title | Human T lymphotropic virus type-1-associated myelopathy manifesting shortly after living-donor renal transplantation. |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Nagamine Y, Hayashi T, Kato Y, Horiuchi Y, Tanahashi N |
| Journal | Internal medicine (Tokyo, Japan)// Intern Med |
| Volume | 54 |
| Issue | 1 |
| Pagination | 75 - 8 |
| Date Published | 2015// |
| ISBN Number | 1349-7235 |
| Other Numbers | bd6, 9204241 |
| Keywords | *Antiviral Agents/tu [Therapeutic Use], *Human T-lymphotropic virus 1/py [Pathogenicity], *Interferon-alpha/tu [Therapeutic Use], *Kidney Transplantation/ae [Adverse Effects], *Living Donors, *Paraparesis, Tropical Spastic/dt [Drug Therapy], *Paraparesis, Tropical Spastic/vi [Virology], Adult, Female, Humans, Paraparesis, Tropical Spastic/di [Diagnosis], Treatment Outcome |
| Abstract | A 38-year-old woman experienced numbness in both lower extremities and spastic paralysis a few months after undergoing living-donor renal transplantation. The patient was negative for human T lymphotropic virus type-1 (HTLV-1) antibodies prior to the procedure; however, she was diagnosed with HTLV-1-associated myelopathy (HAM) based on positive serum and cerebrospinal fluid antibody titers after the surgery. Because the donor was also positive for HTLV-1 antibodies, the infection likely originated from the transplanted kidney. Clinical and imaging improvements were noted following the administration of interferon-alpha. HAM has been reported to occur after living-donor renal transplantation; however, there are no previous reports of onset within such a short period. |
| Notify Library Reference ID | 4505 |
