Real-Time Polymerase Chain Reaction in Stool Detects Transmission of Strongyloides stercoralis from an Infected Donor to Solid Organ Transplant Recipients. 94(4):897-9, 2016

TitleReal-Time Polymerase Chain Reaction in Stool Detects Transmission of Strongyloides stercoralis from an Infected Donor to Solid Organ Transplant Recipients. 94(4):897-9, 2016
Publication TypeJournal Article
Year of Publication2016
AuthorsGómez-Junyent J, Paredes-Zapata D, Parras ER, González-Costello J, Ruiz-Arranz Á, Cañizares R, Saugar JM, Muñoz J
Volume94
Issue4
Pagination7
Abstract

Solid organ transplant recipients can acquire Strongyloides stercoralis from an infected donor. The diagnosis of S. stercoralis in immunocompromised individuals may be challenging due to a lower sensitivity of available parasitological and serological methods, compared with immunocompetent individuals. Recently, a real-time polymerase chain reaction (RT-PCR) in stool has been developed for S. stercoralis diagnosis. We report two cases of S. stercoralis infection transmitted by a donor to two solid organ transplant recipients, who were diagnosed with RT-PCR in stool. This test could play an important role inS. stercoralis diagnosis in immunosuppressed patients, facilitating rapid treatment initiation and reducing the risk of severe strongyloidiasis. Adherence to current recommendations of screening among donors and recipients from endemic areas is also urgently needed.

DOI10.4269/ajtmh.15-0610
Alternate JournalAm J Trop Med Hyg
Notify Library Reference ID4678

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