Recipient morbidity after living and deceased donor liver transplantation: findings from the A2ALL Retrospective Cohort Study

TitleRecipient morbidity after living and deceased donor liver transplantation: findings from the A2ALL Retrospective Cohort Study
Publication TypeJournal Article
Year of Publication2008
AuthorsFreise CE, Gillespie BW, Koffron AJ, Lok AS, Pruett TL, Emond JC, Fair JH, Fisher RA, Olthoff KM, Trotter JF, Ghobrial RM, Everhart JE
JournalAm J Transplant
Volume8
Issue12
Pagination2569 - 79
Date PublishedDec
ISSN1600-6143 (Electronic) 1600-6135 (Linking)
Accession Number18976306
KeywordsAdult, Cohort Studies, Female, Humans, Liver Transplantation / *adverse effects, Living Donors / *statistics & numerical data, Male, Middle Aged, Retrospective Studies, Risk Factors, Thrombosis / epidemiology / etiology, Tissue Donors / *statistics & numerical data, Transplantation / *statistics & numerical data, Treatment Outcome
Abstract

Patients considering living donor liver transplantation (LDLT) need to know the risk and severity of complications compared to deceased donor liver transplantation (DDLT). One aim of the Adult-to-Adult Living Donor Liver Transplantation Cohort Study (A2ALL) was to examine recipient complications following these procedures. Medical records of DDLT or LDLT recipients who had a living donor evaluated at the nine A2ALL centers between 1998 and 2003 were reviewed. Among 384 LDLT and 216 DDLT, at least one complication occurred after 82.8% of LDLT and 78.2% of DDLT (p = 0.17). There was a median of two complications after DDLT and three after LDLT. Complications that occurred at a higher rate (p 40). In summary, complication rates were higher after LDLT versus DDLT, but declined with center experience to levels comparable to DDLT.

DOI10.1111/j.1600-6143.2008.02440.x
Notify Library Reference ID547

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