Postkeratoplasty endophthalmitis by Alcaligenes faecalis: a case report

TitlePostkeratoplasty endophthalmitis by Alcaligenes faecalis: a case report
Publication TypeJournal Article
Year of Publication2002
AuthorsKhokhar DS, Sethi HS, Kumar H, Sudan R, Sharma N, Nayak N
Pagination232 - 3
Date PublishedMar
ISSN0277-3740 (Print) 0277-3740 (Linking)
Accession Number11862104
Keywords*Keratoplasty, Penetrating, Aged, Alcaligenes / *isolation & purification, Anti-Bacterial Agents, Drug Resistance, Microbial, Drug Therapy, Combination / therapeutic use, Endophthalmitis / diagnosis / drug therapy / *microbiology, Eye Infections, Bacterial / diagnosis / drug therapy / *microbiology, Female, Gram-Negative Bacterial Infections / diagnosis / drug therapy / *microbiology, Humans, Microbial Sensitivity Tests, Postoperative Complications / diagnosis / drug therapy / *microbiology

PURPOSE: To describe a postkeratoplasty endophthalmitis owing to Alcaligenes faecalis that resolved with medical management. METHODS: Case report and review of literature. RESULTS: To best of our knowledge, postkeratoplasty endophthalmitis caused by A. faecalis has not been reported in literature. The source of infection was found to be the donor tissue. The organism isolated was resistant to gentamicin, which was the only antibiotic present in the storage medium (McCarey and Kaufman medium). The patient was treated aggressively with topical, systemic and intravitreal antibiotics. The endophthalmitis resolved completely within two weeks. CONCLUSION: A. faecalis is a gram negative, non-spore forming rod that can cause endophthalmitis if donor tissue is contaminated with the organism. Clinical suspicion, review of bacterial culture and sensitivity report from donor tissue, anterior chamber and vitreous taps, along with early therapy with appropriate antibiotics can lead to resolution of infection.

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