Metastatic RCC arising in a transplant kidney

TitleMetastatic RCC arising in a transplant kidney
Publication TypeJournal Article
Year of Publication1998
AuthorsKunisch-Hoppe M, Hoppe M, Bohle RM, Rauber K, Weimar B, Friemann S, Stahl U, Rau WS
JournalEur Radiol
Volume8
Issue8
Pagination1441 - 3
ISSN0938-7994 (Print) 0938-7994 (Linking)
Accession Number9853232
KeywordsAntineoplastic Agents / therapeutic use, Carcinoma, Renal Cell / diagnosis / *secondary / therapy, DNA, Neoplasm / analysis, Female, Follow-Up Studies, Humans, Interferon-alpha / therapeutic use, Interleukin-2 / therapeutic use, Kidney Neoplasms / *etiology / *pathology / therapy, Kidney Transplantation / *adverse effects / pathology, Lumbar Vertebrae, Lymph Nodes / pathology / radiography, Lymphatic Metastasis, Male, Middle Aged, Polymerase Chain Reaction, Renal Dialysis, Sex Chromosomes / genetics, Spinal Neoplasms / diagnosis / *secondary / therapy, Tissue Donors
Abstract

We report a case of metastatic renal cell carcinoma arising in a cadaver transplant kidney 6 years after transplantation. Due to molecular analysis of the tumor tissue we could prove that the carcinoma originated from the male donor. After tumor resection and interruption of immunotherapy, the concomitant bone and lymph node metastases resolved with alpha-interferon and interleukin-2-based immunotherapy.

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