Transient neutropenia in normal donors after G-CSF mobilization and stem cell apheresis

TitleTransient neutropenia in normal donors after G-CSF mobilization and stem cell apheresis
Publication TypeJournal Article
Year of Publication1996
AuthorsAnderlini P, Przepiorka D, Seong D, Champlin R, Korbling M
JournalBritish Journal of Haematology
Volume94
Issue1
Pagination155 - 8
Keywords*Granulocyte Colony-Stimulating Factor / pd [Pharmacology], *Hematopoietic Stem Cell Transplantation / ae [Adverse Effects], *Neutropenia / et [Etiology], Adolescent, Adult, Blood Component Removal / ae [Adverse Effects], Female, Granulocyte Colony-Stimulating Factor / ae [Adverse Effects], Hematopoietic Stem Cell Transplantation / mt [Methods], Humans, Male, Middle Aged, Tissue Donors, Transplantation, Autologous
Abstract

Thirteen normal adult donors underwent daily leukapheresis for peripheral blood progenitor cell collection for allografting beginning on day 4 or 5 of G-CSF mobilization (12 micrograms/kg/d). They had complete blood counts performed 7-10 d after the completion of the procedure. A reduction in the total leucocyte count below baseline levels, accounted for by a decrease in the absolute neutrophil (ANC) and lymphocyte counts, was noted. Neutropenia (ANC

Short TitleTransient neutropenia in normal donors after G-CSF mobilization and stem cell apheresis
Notify Library Reference ID70

Related Incidents